Experiment 941289
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Aegle marmelos (RUTACEAE) |
| Citation | YADAV,SK: JAIN,AK: TRIPATHI,SN: GUPTA,JP:. (1989). IRRITABLE BOWEL SYNDROME: THERAPEUTIC EVALUATION OF INDIGENOUS DRUGS.. 90() |
| Amount utilized | |
| Compound isolated | |
| Disease | 169 PATIENTS WERE GIVEN STANDARD THERAPY, AEGLE MARMELOS & HERPESTIS MONNIERA, OR PLACEBO FOR IRRITABLE BOWEL SYNDROME, IN A RANDOMIZED DOUBLE BLIND TRIAL FOR 6 WEEKS. THE HERBAL PREPARATION WAS JUDGED EFFECTIVE IN 65% OF 57 PATIENTS. THE STANDARD TREATMENT WAS EFFECTIVE IN 47/60 PATIENTS. THE PLACEBO WAS EFFECTIVE IN 17/50 PATIENTS. HERBAL THERAPY WAS MORE EFFECTIVE IN DIARRHEA-PREDOMINANT PATIENTS, WHEREAS STANDARD THERAPY WAS MORE EFFECTIVE IN THE PAINFUL FORM OF DISEASE. NO DIFFERENCES WERE SEEN IN TIME TO RELAPSE. IN THE GASEOUS FORM OF THE DISEASE, NEITHER TREATMENT DIFFERED FROM PLACEBO. DOSING WAS 3 TIMES DAILY. |
| Dose amount | 3.0 GM |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | PERSON |
| Dose expression | DOSE |
| Extract | POWDER |