Experiment 945058

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

XESTOQUINONE

Details

PropertyValue
Pharmacology
CYCLIC AMP STIMULATION
OrganismEmpty organism
CitationKOBAYASHI,M: NAKAMURA,H: KOBAYASHI,J: OHIZUMI,Y:. (1991). MECHANISM OF INOTROPIC ACTION OF XESTOQUINONE, A NOVEL CARDIOTONIC AGENT ISOLATED FROM A SEA SPONGE.. 257(1)
Amount utilized
Compound isolated
DiseaseCYCLIC-AMP CONTENT OF MUSCLE CELLS INCREASED LINEARLY MORE THAN 20 MIN AFTER EXPOSURE TO COMPOUND, WHEREAS INOTROPIC EFFECT SEEN WITHIN 5 MIN.
Dose amount2.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalGUINEA PIG
Dose expressionED50