Experiment 947114

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STAUROSPORINE

Details

PropertyValue
Pharmacology
STEROIDOGENESIS INHIBITION
OrganismEmpty organism
CitationELLIOTT,ME: JONES,HM: TOMASKO,S: GOODFRIEND,TL:. (1991). SPHINGOSINE INHIBITS ANGIOTENSIN-STIMULATED ALDOSTERONE SYNTHESIS.. 38(4)
Amount utilized
Compound isolated
DiseaseVS.DIBUTYRYL CYCLIC AMP-INDUCED ALDOSTERONE SYNTHESIS IN GLOMERULOSA CELLS. INHIBITION OCCURS IN CONVERSION OF CHOLESTEROL TO PREGNENOLONE. IC-50 IS GREATER THAN 300.0 NANOMOLAR.
Number2
Qualitative resultACTIVE
AnimalSTEER
Dose expressionCONC USED