Experiment 951663
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Picrorhiza kurroa (SCROPHULARIACEAE) |
| Citation | DWIVEDI,Y: RASTOGI,R: SHARMA,SK: MEHROTRA,R: GARG,NK: DHAWAN,BN:. (1991). PICROLIV PROTECTS AGAINST MONOCROTALINE-INDUCED HEPATIC DAMAGE IN RATS.. 23(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | VS.MONOCROTALINE-INDUCED HEPATOTOXICITY. HEPATIC SUCCINATE DEHYDROGENASE, ACID RIBONUCLEASE, ACID PHOSPHATASE, GAMMAGLUTAMYL TRANSPEPTIDASE AND 5'-NUCLEOTIDASE LEVELS WERE ALL INCREASED. THE ACTIVITIES OF GLUCOSE-6-PHOSPHATASE AND CYTOCHROME P450 WERE ALL INCREASED. THE LEVELS OF DNA, RNA, GLYCOGEN, ALBUMIN AND PROTEIN WERE ALL INCREASED. SERUM BILIRUBIN LEVELS WERE DECREASED. |
| Dose amount | 25.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |
| Extract | ETOH(95%)EXT |