Experiment 952563
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Gymnodinium breve (GYMNODINIACEAE) |
| Citation | RICHARDS,IS: KULKARNI,AP: BROOKS,SM: PIERCE,R:. (1990). FLORIDA RED-TIDE TOXINS(BREVETOXINS) PRODUCE DEPOLARIZATION OF AIRWAY SMOOTH MUSCLE.. 28(9) |
| Amount utilized | |
| Compound isolated | |
| Disease | CONCENTRATIONS OF 0.01-0.07 MICROGRAM/ML OF GIVEN COMPOUND CAUSED A CONCENTRATION-DEPENDENT DEPOLARIZATION AND CONTRACTION IN GIVEN SMOOTH MUSCLE. THIS RESPONSE WAS NOT SEEN IN THE PRESENCE OF ATROPINE, TETRODOTOXIN, VERAPAMIL OR THE ABSENCE OF CALCIUM. |
| Dose amount | VAR |
| Number | 4 |
| Qualitative result | ACTIVE |
| Animal | DOG |
| Dose expression | CONC USED |