Experiment 954816

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PYRROLOMYCIN B

Details

PropertyValue
Pharmacology
DEGRANULATION INHIBITION
OrganismEmpty organism
CitationMASUDA,K: SUZUKI,K: ISHIDA-OKAWARA,A: MIZUNO,S: HOTTA,K: MIYADOH,S: HARA,O: KOYAMA,M:. (1991). PYRROLOMYCIN GROUP ANTIBIOTICS INHIBIT SUBSTANCE P-INDUCED RELEASE OF MYELOPEROXIDASE FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES.. 44(5)
Amount utilized
Compound isolated
DiseaseVS.MYELOPEROXIDASE RELEASE INDUCED BY MIXTURE OF FORMYL-MET-LEU-PHE AND CYTOCHALASIN B. TREATMENT YEILDED 77.0% OF MYELOPEROXIDASE ACTIVITY SEEN IN CONTROLS, AS ASSAYED SPECTROPHOTOMETRICALLY.
Dose amount0.1 MCG
Number2
Qualitative resultACTIVE
AnimalHUMAN ADULT
Per unitML
Dose expressionCONC USED