Experiment 954942
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Empty organism |
| Citation | MATSUZAKI,Y: MATSUZAKI,T: ONO,H: KOGUCHI,S: TAKEDA,SHU: TAKEDA,SHI: FUNO,S: ABURADA,M: HOSOYA,E: OYAMA,T:. (1991). STUDIES ON THE METABOLIC FATE OF GOMISIN A (JTN-101). II. ABSORPTION AND EXCRETION IN CCI TREATED RATS.. 111(9) |
| Amount utilized | |
| Compound isolated | |
| Disease | TERMINAL HALF-LIFE WAS 0.75 HOUR IN CONTROLS AND 1.5 HOUR IN CCL-4-TREATED ANIMALS. MEAN AREA-UNDER-CURVE FOR LATTER ANIMALS WAS TWICE THAT IN CONTROLS. CUMULATIVE BILIARY EXCRETION IN TREATED ANIMALS WAS 2.5 TIMES THAT IN NORMALS. |
| Dose amount | 5.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |