Experiment 955450
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | REEN,RK: SINGH,J:. (1991). IN VITRO AND IN VIVO INHIBITION OF PULMONARY CYTOCHROME P450 ACTIVITIES BY PIPERINE, A MAJOR INGREDIENT OF PIPER SPECIES.. 29(6) |
| Amount utilized | |
| Compound isolated | |
| Disease | ARYLHYDROCARBON HYDROXYLASE AND 7-ETHOXYCOUMARIN DEETHYLASE WERE NONCOMPETITIVELY INHIBITED BY 50%. 3-METHYLCHOLANTHRENE INDUCTION OF THESE ENZYMES DID NOT ALTER THIS INHIBITION. |
| Dose amount | 100.0 MICROMOLS |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Dose expression | CONC USED |