Experiment 955477
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV INFUSION |
| Organism | Empty organism |
| Citation | BROWN,T: HAVLIN,K: WEISS,G: CAGNOLA,J: KOELLER,J: KUHN,J: RIZZO,J: CRAIG,J: PHILLIPS,J: VON HOFF,D:. (1991). A PHASE I TRIAL OF TAXOL GIVEN BY A 6-HOUR INTRAVENOUS INFUSION.. 9(7) |
| Amount utilized | |
| Compound isolated | |
| Disease | 31 PATIENTS WERE USED IN THIS PHASE 1 STUDY. PATIENTS WERE GIVEN DOSES RANGING FROM 175 MG/SQ M TO 275 MG/SQ M ADMINISTERED OVER A 6 HOUR PERIOD EVERY 21 DAYS. TOXICITIES INCLUDED MYELOSUPPRESSION, FATALITIES DUE TO SEPSS, MUCOSITIS, NEUROPATHY, NAUSEA, VOMITING, DIARRHEA, ALOPEICA AND FEVER. |
| Dose amount | VAR |
| Number | 1 |
| Qualitative result | . |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |