Experiment 958183
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Empty organism |
| Citation | CHU,PS: SEGALL,HJ:. (1991). SPECIES DIFFERENCE IN THE URINARY EXCRETION OF ISATINECIC ACID FROM THE PYRROLIZIDINE ALKALOID RETRORSINE.. 100(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | CMPD WAS METABOLIZED TO A LESSER EXTENT TO ISATINECIC ACID AND PYRROLIC METABOLITES AND TO A GREATER EXTENT TO THE N-OXIDE, IN GUINEA PIGS COMPARED TO MICE, HAMSTERS AND RATS. GUINEA PIGS ARE LESS SUSCEPTIBLE TO PYRROLIZIDINE ALKALOID POSIONING. |
| Dose amount | 25.0 MG |
| Number | 1 |
| Qualitative result | . |
| Animal | GUINEA PIG |
| Per unit | KG |
| Dose expression | DOSE |