Experiment 958417
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Tripterygium wilfordii (CELASTRACEAE) |
| Citation | XU,Y: WANG,SW: ZHONG,CQ: QIAN,SZ:. (1988). REVERSIBILITY OF INFERTILITY INDUCED BY LEIGONGTENG GLYCOSIDES.. 23(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | ADMINISTRATION WAS DAILY FOR 6 DAYS PER WEEK FOR 12 WEEKS. INFERTILITY WAS INDUCED IN ALL RATS AFTER TREATMENT FOR 8 WEEKS. FERTILITY WAS NORMALIZED 5 WEEKS AFTER DISCONTINUATION OF TREATMENT. PARAMETERS INCLUDING HISTOLOGY OF TESTES, ACTIVITY + DENSITY OF SPERM IN EPIDIDYMIS, SERUM TESTOSTERONE, NA+ AND K+, WEIGHT OF ACCESSORY SEX ORGANS, BLOOD PICTURE & HISTOLOGY OF MAJOR ORGANS WERE NOT FOUND SIGNIFICANTLY DIFFERENT FROM CONTROLS. LONG TERM REVERSIBILITY, HOWEVER, WAS NOT STUDIED. |
| Dose amount | 10.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | ANIMAL |
| Dose expression | DOSE |
| Extract | CHROMATOGRAPHIC FRACTION |
| Gender | MALE |