Experiment 958428
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Tripterygium wilfordii (CELASTRACEAE) |
| Citation | WANG,YJ: XU,L: WANG,C: ZHU,CF:. (1988). DECREASE PROTEINURIA IN GLOMERULAR DISEASE WITH SHENTENG SYRUP.. 23(6) |
| Amount utilized | |
| Compound isolated | |
| Disease | 15 CASES OF CHRONIC NEPHRITIS, 1 CASE OF HYPERTENSIVE NEPHRITIS, 8 CASES OF LATENT NEPHRITIS, 2 CASES EACH OF NEPHROTIC SYNDROME TYPES I AND II AND 2 CASES OF LUPUS NEPHRITIS WERE TREATED WITH A SYRUP MADE FROM THE TITLE PLANT. THE SYRUP ALSO CONTAINED TRIPTERYGIUM WILFORDII, SALVIA MILTIORRHIZA AND GLYCYRRHIZA GLABRA. DOSAGE WAS 10 ML 3-4 TIMES DAILY. STEROIDS WERE GRADUALLY WITHDRAWN IN PATIENTS WITH TYPE II NEPHROTIC SYNDROME BUT STOPPED IN OTHER PATIENTS. THE COURSE OF TREATMENT RANGED FROM 2 MONTHS TO OVER 10 MONTHS. PROTEINURIA WAS IMPROVED IN ALL PATIENTS. THE ONSET OF ACTION WAS 2-3 WEEKS. IN 10 CASES WITH PROTEINURIA CHECKED BEFORE AND AFTER TREATMENT, PROTEINURIA WAS FOUND DECREASED FROM 4.1 TO 1.4 GM/DL. PROTEINURIA DISAPPEARED IN 12 PATIENTS. |
| Dose amount | 10.0 ML |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | PERSON |
| Dose expression | DOSE |
| Extract | DECOCTION |