| Disease | REVIEW ON THE CHINESE USE OF THE TITLE PLANT IN TREATING BECHCET'S DISEASE, PSORITIC ARTHRITIS, PUSTULAR PSORIASIS, DISCOID AND SYSTEMIC LUPUS ERYTHEMATOSUS, ALLERGIC ANGIITIS, SWEET'S SYNDROME, LEPRA REACTIONS, ECZEMA AND DERMATITIS.
ALSO: PALMOPLANTAR PUSTULOSIS, ERYTHEMA MULTIFORME AND ERYTHEMA NODOSUM, RECURRENT APHTHOUS ULCERS AND PSORIASIS VULGARIS.
THE MOST COMMON SIDE EFFECTS REPORTED ARE GASTROINTESTINAL DISORDERS INCLUDING NAUSEA, VOMITING, ANOREXIA, BURNING SENSATION OF THE LOWER ESOPHOGUS, XEROSTOMIA, DIARRHEA AND CONSTIPATION.
MOST OF THESE SUBSIDED SPONTANEOUSLY AND IT WAS NOT NECESSARY TO DISCONTINUE THE DRUG. LEUKOPENIA AND THROMBOCYTOPENIA WERE OBSERVED IN A FEW PATIENTS, BUT THEY REVERTED TO NORMAL SHORTLY AFTER DISCONTINUATION OF THE DRUG.
DIZZINESS, FATIGUE AND DROWSINESS OCCURRED IN SOME PATIENTS. MUCOCUTANEOUS REACTIONS REPORTED INCLUDED ECZEMATOID DERMATITIS, PIGMENTATION AND XEROSIS OF THE SKIN, PRURITUS, PERIORAL HERPES SIMPLEX, ORAL ULCERS AND ALOPECIA.
IRREGULARITY OF MENSTRUATION AND AMENORRHEA HAVE BEEN REPORTED; THESE REACTIONS USUALLY DISAPPEARED AFTER STOPPING THE DRUG. SIDE EFFECTS OF TOTAL GLYCOSIDES WERE LESS THAN AND MILDER THAN THOSE OF CRUDE PREPARATIONS OF TRIPTERYGIUM. (37 REFS). |