Experiment 960053
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | EXTERNAL |
| Organism | Empty organism |
| Citation | SIMONE,DA: OCHOA,J:. (1991). EARLY AND LATE EFFECTS OF PROLONGED TOPICAL CAPSAICIN ON CUTANEOUS SENSIBILITY AND NEUROGENIC VASODILATATION IN HUMANS.. 47(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | SALVE CONTAINING GIVEN COMPOUND WAS APPLIED 4 TIMES DAILY FOR 6 WEEKS. A DESENSITIZATION OF HEAE-SENNSITIVE NOCICEPTORS WAS NOTED WHICH REVERSED UPON DISCONTINUATION OF TREATMENT. PAIN THRESHOLD TEMPERATURE WAS ELEVATED 3.5 C AFTER 6 WEEKS OF TREATMENT DETECTION THRESHOLDS FOR TOUCH, COLD SENSATION, COLD-INDUCED PAIN AND MECHANICAL SENSATION WERE UNCHANGED. |
| Dose amount | 0.075 |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |