Experiment 961223
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ROUTE NOT GIVEN |
| Organism | Tripterygium wilfordii (CELASTRACEAE) |
| Citation | ZHENG,JR:. (1983). TOXICOLOGY OF TRIPTERYGIUM TOTAL GLYCOSIDES.. 5(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE "TOTAL GLYCOSIDES" OF THIS PLANT WERE FOUND TO DECREASE THE BODY WEIGHT BUT DID NOT AFFECT THE FUNCTION OF HEART, LIVER AND KIDNEY SIGNIFICANTLY. THE REPRODUCTIVE EPITHELIA OF THE TESTIS WAS DAMAGED WITH AN INHIBITION OF THE DIVISION OF SPERMATOGONIA, LEADING TO A REDUCTION AND DISSAPEARANCE OF VARIOUS REPRODUCTIVE CELLS. THE SAFETY RANGE OF THIS PREPARATION WAS ONE FOLD HIGHER THAN THAT OF THE CRUDE DRUGS. |
| Number | 6 |
| Qualitative result | WEAK ACTIVITY |
| Animal | RAT |
| Dose expression | DOSE |
| Extract | CHROMATOGRAPHIC FRACTION |
| Gender | MALE |