Experiment 962195

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CAMPTOTHECIN

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationHERTZBERG,RP: CARANFA,MJ: HOLDEN,KG: JAKAS,DR: GALLAGHER,G: MATTERN,MR: MONG,SM: BARTUS,JO: JOHNSON,RK: KINGSBURY,WD:. (1989). MODIFICATION OF THE HYDROXY LACTONE RING OF CAMPTOTHECIN: INHIBITION OF MAMMALIAN TOPOISOMERASE I AND BIOLOGICAL ACTIVITY.. 32(3)
Amount utilized
Compound isolated
Dose amount0.014 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50