Experiment 96267

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

TROPOLONE,3-7-DIHYDROXY:

Alerts

DOSING ON DAYS 1-9.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismStreptomyces tropolofaciens (STREPTOMYCETACEAE)
CitationSUGAWARA,K: OHBAYASHI,M: SHIMIZU,K: HATORI,M: KAMEI,H: KONISHI,M: OKI,T: KAWAGUICHI,H:. (1988). BMY-28438 (3,7-DIHYDROXYTROPOLONE), A NEW ANTITUMOR ANTIBIOTIC ACTIVE GAINST B16 MELANOMA I. PRODUCTION, ISOLATION, STRUCTURE AND BIOLOGICAL ACTIVITY.. 41(7)
Amount utilized
Compound isolated
Dose amount1.3 MG
Number19
Percent yield81%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS