Experiment 966233

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

GRISEOLIC ACID

Details

PropertyValue
Pharmacology
PHOSPHODIESTERASE INHIBITION
OrganismEmpty organism
CitationMISHIMA,HK: KIUCHI,Y: YOKOYAMA,T: YASUMOTO,T: YAMAZAKI,M:. (1991). A CYCLIC AMP PHOSPHODIESTERASE INHIBITOR, 8'-PIVALOYLOXYMETHYL ESTER (POM-ESTER) OF GRISEOLIC ACID, LOWERS RABBIT INTRAOCULAR PRESSURE.. 10(9)
Amount utilized
Compound isolated
DiseaseENZYME WAS PREPARED FROM RABBIT CILIARY BODY. EFFECT OF 8'-PIVOLYLOXYMETHYL ESTER OF CMPD WAS ASSAYED.
Dose amount2.4 MICROMOLS
Number6
Qualitative resultACTIVE
Dose expressionIC50