Experiment 970865
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | SANO,T: MORISHITA,Y: MATSUDA,Y: YAMADA,K:. (1992). PHARMACOLOGICAL PROFILE OF HS-142-1 , A NOVEL NONPEPTIDE ATRIAL NATRIURETIC PEPTIDE ANTAGONIST OF MICROBIAL ORIGIN. I. SELECTIVE INHIBITION OF THE ACTIONS OF NATRIURETIC PEPTIDES IN ANESTHETIZED RATS.. 260(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | CMPD INHIBITED HUMAN ATRIAL NATURIURETIC PEPTIDE-INDUCED DIURESIS, NATRIURESIS AND INCREASED URINARY CGMP. HYPOTENSIVE RESPONSES TO ANP WAS ONLY SLIGHTLY INHIBITED. |
| Dose amount | 1.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |