Experiment 972155

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

WORTMANNIN

Details

PropertyValue
Pharmacology
MYOSIN LIGHT CHAIN KINASE INHIBITION
OrganismTalaromyces wortmannin (TRICHOCOMACEAE)
CitationNAKANISHI,S: KAKITA,S: TAKAHASHI,I: KAWAHARA,K: TSUKUDA,E: SANO,T: YAMADA,K: YOSHIDA,M: KASE,H: MATSUDA,Y:. (1992). WORTMANNIN, A MICROBIAL PRODUCT INHIBITOR OF MYOSIN LIGHT CHAIN KINASE.. 267(4)
Amount utilized
Compound isolated
DiseaseTHE INHIBITIONOF MYOSIN LIGHT CHAIN KINASE WAS PREVENTED BY HIGH CONCENTRATIONS OF ATP.
Dose amount0.17 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50