Experiment 972845
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Schisandra chinensis (SCHISANDRACEAE) |
| Citation | FANG,J: JIANG,J: LU,DC:. (1987). EFFECT OF SHENGMAI FLUID ON LEFT VENTRICULAR FUNCTION IN PATENTS WITH CORONARY DISEASE: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, CROSS TRIAL.. 26(7) |
| Amount utilized | |
| Compound isolated | |
| Disease | THIRTY-ONE CASES OF MYOCARDIAL INFARCTION AND NINE CASES OF CHRONIC STABLE ANGINA PECTORIS WERE RANDOMLY DIVIDED INTO 2 GROUPS OF 20 PATIENTS EACH. ALL MEDICATIONS WERE WITHDRAWN 7 DAYS BEFORE THESE PATIENTS ENTERED INTO THE DOUBLE-BLIND STUDY. EVERY PATIENT WAS GIVEN SEPARATELY THE SHENGMAI FLUID AND A PLACEBO AT 10 ML TWICE DAILY FOR 20 DAYS WITH A WASHOUT PERIOD OF 10 DAYS IN BETWEEN. THE HEATHER INDEX, STROKE INDEX, CARDIAC INDEX AND ADZ/DT(MAX) AND Q-B/B/X IN IMPEDENCE CARDIOGRAM WERE MEASURED BEFORE AND AFTTER DRUG ADMINSTRATION. SHENGMAI FLUID INCREASED THE FIRST 3 PARAMETERS AND DECREASED THE LAST 2 PARAMETERS, IT IS EFFECTIVE IN IMPROVING THE LEFT VENTRIVULAR SYSTOLIC FUNCTION AND DIASTOLIC COMPLIANCE. THE RESULTS WERE OBTAINED USING A TRADITIONAL CHINESE FORMULA SHENGMAI, WHICH CONSISTS OF PANAX GINSENG ROOTS AND SCHISANDRA CHINENSIS FRUITS. |
| Dose amount | 10.0 ML |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | PERSON |
| Dose expression | DOSE |
| Extract | DECOCTION |