Experiment 975705
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Empty organism |
| Citation | WONG,CW: SEOW,WK: THONG,YH:. (1992). COMPARATIVE EFFECTS OF TETRANDRINE AND BERBAMINE ON ACUTE AND RELAPSING EXPERMINTAL ALLERGIC ENCEPHALITIS IN LEWIS RATS.. 97(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | ALLERGIC ENCEPHALITIS WAS INDUCED VIA SENSITIZATION TO GUINEA PIG SPINAL CORD HOMOGENATE AND M. TUBERCULOSIS MIXTURE. DOSE OF CMPD WAS GIVEN ON ALTERNATE DAYS BEGINNING 6 DAYS BEFORE INDUCTION OF ALLERGY TO 36 DAYS POST INDUCTION. THE ONSET WAS DELAYED AND THE SEVERITY AND DURATION DECREASED OF THE ACUTE REACTION (12-14 DAYS) WHILE THE INCIDENCE AND SEVERITY WERE DECREASED AND ONSET DELAYED OF RELAPSE (20-24 DAYS.). |
| Dose amount | 60.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |