Experiment 981897

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODEISOLATION AND IDENTIFICATION OF

Compounds isolated

MAYTANSINOL ISO-BUTYRATEMAYTANSINOL ISO-VALERATE

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismNocardia species (NOCARDIACEAE)
CitationOOTSU,K: KOZAI,Y: IKEYAMA,S: TAKEUCHI,M: SUGINO,Y: TASHIRO,T: TSUKAGOSHI,S: SAKURAI,Y:. (1978). ANTITUMOR ACTIVITY OF A NEWLY ISOLATED ANTIMITOTIC ANTIBIOTIC, ANSAMITOCIN.. 1978()
Amount utilized
Compound isolated
Dose amount0.8 MCG
Number1
Percent yield130%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS