Experiment 98343

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PHORBOL,12-DEOXY-16-HYDROXY: 4'-(12'-14'-BUTADIENYL)-6'-(16'-18'-20'-NONATRIENYL)-BICYCLOHEXANE-(13-O)-2'-(CARBOXYLATE)-(16-O)-3'-(8'-BUTENOIC-10')ATE

Details

PropertyValue
Pharmacology
HYDROXYMETHYLGLUTARYL-CO-A REDUCTASE INDUCTION
OrganismJatropha curcas (EUPHORBIACEAE)
CitationHIROTA,M: SUTTAJIT,M: SUGURI,H: ENDO,Y: SHUDO,K: WONGCHAI,V: HECKER,E: FUJIKI,H:. (1988). A NEW TUMOR PROMOTER FROM THE SEED OIL OF JATROPHA CURCAS L., AN INTRAMOLECULAR DIESTER OF 12-DEOXY-16-HYDROXYPHORBOL.. 48(20)
Amount utilized
Compound isolated
DiseaseTPA BINDING WAS INHIBITED.
Dose amount17.0 NANOMOLS
Number3
Qualitative resultACTIVE
Dose expressionIC50