Experiment 987918

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ETOPOSIDE*

Details

PropertyValue
Pharmacology
TUBULIN POLYMERIZATION INHIBITION
OrganismEmpty organism
CitationBREWER,CF: LOIKE,KD: HORWITZ,SB: STERNLICHT,H: GENSLER,WJ:. (1979). CONFORMATIONAL ANALYSIS OF PODOPHYLLOTOXIN AND ITS CONGENERS STRUCTURE-ACTIVITY RELATIONSHIP IN MICROTUBULE ASSEMBLY.. 22()
Amount utilized
Compound isolated
Dose amount>1.0 MILLIMOLS
Number1
Qualitative resultWEAK ACTIVITY
AnimalCHICKEN
Dose expressionED50