Experiment 990981
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | KOVACH,JS: AMES,MM: POWIS,G: MOERTEL,CG: HAHN,RG: CREAGAN,ET:. (1979). TOXICITY AND PHARMACOKINETICS OF A PYRROLIZIDINE ALKALOID,INDICINE-N-OXIDE,IN HUMANS.. 39() |
| Amount utilized | |
| Compound isolated | |
| Disease | DAILY DOSING X MAJOR TOXIC EFFECT WAS MYELOSUPRESSION SEVERITY OF MYELOSUPPRESSION WAS ENHANCED IN PATIENTS WHO HAD PRIOR TREATMNT WITH NITROSOUREAS |
| Dose amount | 2.25 GM |
| Number | 3 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |