Experiment 993756

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

HARRINGTONINE

Details

PropertyValue
Pharmacology
TOXIC EFFECT(GENERAL)
Administration routeIV
OrganismEmpty organism
CitationZHANG,Y: YU,H: LUO,X: ZHENG,Y: LI,W: LIU,X: YUAN,Y:. (1979). EXPERIMENTAL STUDIES ON THE TOXICITY OF HARRINGTONINE AND HOMOHARRINGTONINE.. 92()
Amount utilized
Compound isolated
DiseaseDAILY DOSING X 5 2/20 DEATHS:1/20 WEIGHT LOSS MORE THAN 10%:2/20 ANOREXIA:2/20 TACHYCARDIA:2/20 ANEMIA:2/20 LEUKOPENIA:1/20 THROMBOCYTOPENIA:2/20 MYOCARDIAL DEGENERATION:1/20 LIVER CONGESTIONS:2/20 LIVER DEGENERATION:1/20 SPLEEN CONGESTION: 2/20 SPLEEN LYMPHOID DEPLETION IN SPLEEN 1/20 KIDNEY CONGESTION:2/20 KIDNEY DEGENERATION:2/20 PULMONARY EDEMA:1/1 SPERMATOGENESIS SUPPRESSION.
Dose amount1.04 MG
Number3
Qualitative resultEQUIVOCAL
AnimalRABBIT
Per unitKG
Dose expressionDOSE