Experiment 994126
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Aconitum japonicum (RANUNCULACEAE) |
| Citation | HIKINO,H: ITO,T: YAMADA,C: SATO,H: KONNO,C: OHIZUMI,Y:. (1979). VALIDITY OF ORIENTAL MEDICINES. PART 10. PHARMACEUTICAL STUDIES ON ACONITUM ROOTS. PART 7. ANALGESIC PRINCIPLES OF ACONITUM ROOTS.. 2() |
| Amount utilized | |
| Compound isolated | |
| Disease | DRIED ROOTS HEATED AT 100 DEGREES FOR FOUR HOURS PRIOR TO EXTRACTION WITH METHANOL. ALKALOID CONTENT OF ROOTS WAS HYPACONITINE (0.10%), MESACONITINE + ACONITINE (0.07%), BENZOYLHYPACONINE (0.09%) AND BENZOYLMESACONINE + BENZOYLACONINE (0.16%). |
| Dose amount | 1.3 GM |
| Number | 12 |
| Qualitative result | . |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | LD50 |
| Extract | MEOH EXT |