Experiment 994131
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | SC |
| Organism | Aconitum japonicum (RANUNCULACEAE) |
| Citation | HIKINO,H: ITO,T: YAMADA,C: SATO,H: KONNO,C: OHIZUMI,Y:. (1979). VALIDITY OF ORIENTAL MEDICINES. PART 10. PHARMACEUTICAL STUDIES ON ACONITUM ROOTS. PART 7. ANALGESIC PRINCIPLES OF ACONITUM ROOTS.. 2() |
| Amount utilized | |
| Compound isolated | |
| Disease | DRIED ROOTS MIXED WITH 20% WATER AND HEATED AT 100 DEGREES FOR ONE HOUR PRIOR TO EXTRACTION WITH METHANOL. ALKALOID CONTENT OF ROOTS WAS HYPACONITINE (0.11%), MESACONITINE + ACONITINE (0.13%), BENZOYLHYPACONINE (0.07%) AND BENZOYLMESACONINE + BENZOYLACONINE (0.21%). |
| Dose amount | 30.0 MG |
| Number | 17 |
| Qualitative result | EQUIVOCAL |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | DOSE |
| Extract | MEOH EXT |