Experiment 998516
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Cycas circinalis (CYCADACEAE) |
| Citation | SIEBER,SM: CORREA,P: DALGARD,DW: MC INTIRE,KR: ADAMSON,RH:. (1980). CARCINOGENICITY AND HEPATOTOXICITY OF CYCASIN AND ITS AGLYCONE METHYLAZOXYMETHANOL ACETATE IN NONHUMAN PRIMATES.. 65() |
| Amount utilized | |
| Compound isolated | |
| Disease | CYCAD MEAL CONTAINED 3.0% CYCASIN MONKEYS WERE DOSED INITIALLY WITHIN 24 HOURS AFTER BIRTH. DOSING WAS THREE TIMES PER WEEK ON ALTERNATE WEEKS FOR EIGHT MONTHS WELL DIFFERENTIATED HEPATOCELLULAR CARCINOMA:TOXIC HEPATITIS:PNEUMONIA |
| Dose amount | 0.75 GM |
| Number | 4 |
| Qualitative result | ACTIVE |
| Animal | MONKEY(CYNOMOLGUS) |
| Per unit | ANIMAL |
| Dose expression | DOSE |
| Extract | SEEDS |
| Gender | MALE |