Citation 104730

PILCH,DS: YU,C: MAKHEY,D: LA VOIE,EJ: SRINIVASAN,AR: OLSON,WK: SAUERS,RR: BRESLAUER,KJ: GEACINTOV,NE: LIU,LF:. (1997). MINOR GROOVE-DIRECTED AND INTERCALATIVE LIGAND-DNA INTERACTIONS IN THE POISONING OF HUMAN DNA TOPOISOMERASE I BY PROTOBERBERINE ANALOGS.. 36(41)

Citation Details

Title	MINOR GROOVE-DIRECTED AND INTERCALATIVE LIGAND-DNA INTERACTIONS IN THE POISONING OF HUMAN DNA TOPOISOMERASE I BY PROTOBERBERINE ANALOGS.
Authors	PILCH,DS: YU,C: MAKHEY,D: LA VOIE,EJ: SRINIVASAN,AR: OLSON,WK: SAUERS,RR: BRESLAUER,KJ: GEACINTOV,NE: LIU,LF:
Year	1997
Volume	36
Issue	41

Summary

Year: 1997

Journal: Unknown

Organisms and Their Experiments (1)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CORALYNE,8-DEMETHYL:*	WEAK ACTIVITY
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CORALYNE,8-DEMETHYL:*	INACTIVE
3	INTERCALATION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	CORALYNE,8-DEMETHYL:*	WEAK ACTIVITY
4	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CORYALYNE,5-6-DIHYDRO-8-DEMETHYL:*	ACTIVE
5	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CORYALYNE,5-6-DIHYDRO-8-DEMETHYL:*	INACTIVE
6	INTERCALATION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	CORYALYNE,5-6-DIHYDRO-8-DEMETHYL:*	WEAK ACTIVITY
7	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PALMATINE	INACTIVE
8	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PALMATINE	INACTIVE
9	INTERCALATION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	PALMATINE	WEAK ACTIVITY

Citation 104730

Citation Details

Summary

Organisms and Their Experiments (1)

Unknown organism

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