Experiment 369878

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CORALYNE,8-DEMETHYL:*

Details

PropertyValue
Pharmacology
TOPOISOMERASE II INHIBITION
OrganismEmpty organism
CitationPILCH,DS: YU,C: MAKHEY,D: LA VOIE,EJ: SRINIVASAN,AR: OLSON,WK: SAUERS,RR: BRESLAUER,KJ: GEACINTOV,NE: LIU,LF:. (1997). MINOR GROOVE-DIRECTED AND INTERCALATIVE LIGAND-DNA INTERACTIONS IN THE POISONING OF HUMAN DNA TOPOISOMERASE I BY PROTOBERBERINE ANALOGS.. 36(41)
Amount utilized
Compound isolated
DiseaseCOMPOUND WAS TESTED FOR TOPO II POISONING ACTIVITY.
Dose amount26.0 MICROMOLS
Number2
Qualitative resultINACTIVE
Dose expressionCONC USED