Citation 119527

BAI,R: ROACH,MC: JAYARAM,SK: BARKOCZY,J: PETTIT,GR: LUDUENA,RF: HAMEL,E:. (1993). DIFFERENTIAL EFFECTS OF ACTIVE ISOMERS, SEGMENTS, AND ANALOGS OF DOLASTATIN 10 ON LIGAND INTERACTIONS WITH TUBULIN. CORRELATION WITH CYTOTOXICITY.. 45(7)

Citation Details

TitleDIFFERENTIAL EFFECTS OF ACTIVE ISOMERS, SEGMENTS, AND ANALOGS OF DOLASTATIN 10 ON LIGAND INTERACTIONS WITH TUBULIN. CORRELATION WITH CYTOTOXICITY.
AuthorsBAI,R: ROACH,MC: JAYARAM,SK: BARKOCZY,J: PETTIT,GR: LUDUENA,RF: HAMEL,E:
Year1993
Volume45
Issue7

Summary

Year: 1993

Journal: Unknown

Organisms and Their Experiments (1)

Unknown organism

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
SYNTHESIS OF ANALOGSCOMPLETE SYNTHESIS REPORTED
DOLASTATIN 10
None
2
TUBULIN POLYMERIZATION INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
DOLASTATIN 10
ACTIVE
3
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
DOLASTATIN 10
STRONG ACTIVITY
4
TUBULIN BINDING EFFECT
PHARMACOLOGY OF COMPOUND - IN VITRO
DOLASTATIN 10
ACTIVE
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