Experiment 473231

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DOLASTATIN 10

Details

PropertyValue
Pharmacology
TUBULIN BINDING EFFECT
OrganismEmpty organism
CitationBAI,R: ROACH,MC: JAYARAM,SK: BARKOCZY,J: PETTIT,GR: LUDUENA,RF: HAMEL,E:. (1993). DIFFERENTIAL EFFECTS OF ACTIVE ISOMERS, SEGMENTS, AND ANALOGS OF DOLASTATIN 10 ON LIGAND INTERACTIONS WITH TUBULIN. CORRELATION WITH CYTOTOXICITY.. 45(7)
Amount utilized
Compound isolated
DiseaseTHIS ASSAY WAS LOOKING AT VINBLASTINE BINDING TO TUBULIN.
Dose amount6.0 MICROMOLS
Number4
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50