Citation 138733

LINGHAM,RB: SILVERMAN,KC: JAYASURIYA,H: KIM,BM: AMO,SE: WILSON,FR: REW,DJ: SCHABER,MD: BERGSTROM,JD: KOBLAN,KS: GRAHAM,SL: KOHL,NE: GIBBS,JB: SINGH,SB:. (1998). CLAVARIC ACID AND STEROIDAL ANALOGUES AS RAS- AND FPP-DIRECTED INHIBITORS OF HUMAN FARNESYL-PROTEIN TRANSFERASE.. 41(23)

Citation Details

Title	CLAVARIC ACID AND STEROIDAL ANALOGUES AS RAS- AND FPP-DIRECTED INHIBITORS OF HUMAN FARNESYL-PROTEIN TRANSFERASE.
Authors	LINGHAM,RB: SILVERMAN,KC: JAYASURIYA,H: KIM,BM: AMO,SE: WILSON,FR: REW,DJ: SCHABER,MD: BERGSTROM,JD: KOBLAN,KS: GRAHAM,SL: KOHL,NE: GIBBS,JB: SINGH,SB:
Year	1998
Volume	41
Issue	23

Summary

Year: 1998

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARINONE	ACTIVE
2	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARINONE	ACTIVE
3	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARINONE	WEAK ACTIVITY
4	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARINONE	INACTIVE
5	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHAETOMELLIC ACID A	ACTIVE
6	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHAETOMELLIC ACID A	ACTIVE
7	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHAETOMELLIC ACID A	WEAK ACTIVITY
8	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHAETOMELLIC ACID A	WEAK ACTIVITY
9	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OREGANIC ACID	ACTIVE
10	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OREGANIC ACID	ACTIVE
11	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OREGANIC ACID	WEAK ACTIVITY

Clavariadelphus truncatus (CLAVARIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFSYNTHESIS OF ANALOGSMASS-SPECTRAL FRAGMENTATION REPORTED	CLAVARIC ACID	None
2	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARIC ACID	ACTIVE
3	FARNESYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARIC ACID	ACTIVE
4	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARIC ACID	WEAK ACTIVITY
5	GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CLAVARIC ACID	INACTIVE