Experiment 620981

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CHAETOMELLIC ACID A

Details

PropertyValue
Pharmacology
GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION
OrganismEmpty organism
CitationLINGHAM,RB: SILVERMAN,KC: JAYASURIYA,H: KIM,BM: AMO,SE: WILSON,FR: REW,DJ: SCHABER,MD: BERGSTROM,JD: KOBLAN,KS: GRAHAM,SL: KOHL,NE: GIBBS,JB: SINGH,SB:. (1998). CLAVARIC ACID AND STEROIDAL ANALOGUES AS RAS- AND FPP-DIRECTED INHIBITORS OF HUMAN FARNESYL-PROTEIN TRANSFERASE.. 41(23)
Amount utilized
Compound isolated
DiseaseUSING RAS-CAIL AS PEPTIDE SUBSTRATE.
Dose amount38 MICROMOLS
Number7
Qualitative resultWEAK ACTIVITY
Dose expressionIC50