Citation 170471

SIEBER,SM: WOLPERT,MK: ADAMSON,RH: CYSYK,RL: BONO,VH: JOHNS,DG:. (1976). EXPERIMENTAL STUDIES WIH MAYTANSINE-A NEW ANTITUMOR AGENT.. 1976()

Citation Details

Title	EXPERIMENTAL STUDIES WIH MAYTANSINE-A NEW ANTITUMOR AGENT.
Authors	SIEBER,SM: WOLPERT,MK: ADAMSON,RH: CYSYK,RL: BONO,VH: JOHNS,DG:
Year	1976
Volume	1976
Issue

Summary

Year: 1976

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ABORTIFACIENT EFFECT	PHARMACOLOGY OF COMPOUND - IN VIVOANTIFERTILITY	MAYTANSINE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
7	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
8	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	INACTIVE
9	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	INACTIVE
10	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
11	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	INACTIVE
12	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	INACTIVE
13	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	INACTIVE
14	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	INACTIVE
15	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
16	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
17	RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	INACTIVE
18	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
19	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	WEAK ACTIVITY
20	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	WEAK ACTIVITY
21	ANTIMITOTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
22	NEUROTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	MAYTANSINE	INACTIVE
23	NEUROTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	MAYTANSINE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	NEUROTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	VINCALEUKOBLASTINE	INACTIVE
2	NEUROTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	VINCALEUKOBLASTINE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	NEUROTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	LEUROCRISTINE	ACTIVE
2	NEUROTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	LEUROCRISTINE	ACTIVE

Citation 170471

Citation Details

Summary

Organisms and Their Experiments (3)

Unknown organism

Unknown organism

Unknown organism

Show SPARQL Queries (1)

Query 1