Experiment 1079933

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE

Compounds isolated

MAYTANSINE

Details

PropertyValue
Pharmacology
NEUROTOXIC ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationSIEBER,SM: WOLPERT,MK: ADAMSON,RH: CYSYK,RL: BONO,VH: JOHNS,DG:. (1976). EXPERIMENTAL STUDIES WIH MAYTANSINE-A NEW ANTITUMOR AGENT.. 1976()
Amount utilized
Compound isolated
DiseaseDAILY DOSING FOR 5 DAYS RESULTED IN HIND LIMB PARALYSIS IN 50% OF THE ANIMALS.
Dose amount200.0 MCG
Number23
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE