Citation 178964

CRESTEIL,T: LESCA,P:. (1983). ENHANCEMENT OF DNA BINDING, MUTAGENICITY AND CARCINOGENICITY OF POLYCYCLIC AROMATIC HYDROCARBONS AFTER INDUCTION OF CYTOCHROME P-450 BY ELLIPTICINES IN RATS AND MICE.. 47(2)

Citation Details

Title	ENHANCEMENT OF DNA BINDING, MUTAGENICITY AND CARCINOGENICITY OF POLYCYCLIC AROMATIC HYDROCARBONS AFTER INDUCTION OF CYTOCHROME P-450 BY ELLIPTICINES IN RATS AND MICE.
Authors	CRESTEIL,T: LESCA,P:
Year	1983
Volume	47
Issue	2

Summary

Year: 1983

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	ACTIVE
2	BENZPHETAMINE DEMETHYLASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	INACTIVE
3	ETHOXYCOUMARIN DEETHYLASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	ACTIVE
4	BENZOPYRENE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	ACTIVE
5	ACETANILIDE 4-HYDROXYLASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	INACTIVE
6	EPOXIDE HYDRASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	INACTIVE
7	GLUTATHIONE-S-TRANSFERASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	INACTIVE
8	ARYL HYDROCARBON HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ARYL HYDROCARBON HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE,9-HYDROXY:	ACTIVE
2	CARCINOGENIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)	ELLIPTICINE,9-HYDROXY:	INACTIVE
3	COMUTAGENIC ACTIVITY	EFFECTS DUE TO A COMBINATION OF DRUGSPHARMACOLOGY OF COMPOUND - IN VITROCARCINOGENIC DATA (MARKER CODE)	ELLIPTICINE,9-HYDROXY:	ACTIVE
4	COCARCINOGENIC ACTIVITY	EFFECTS DUE TO A COMBINATION OF DRUGSPHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)	ELLIPTICINE,9-HYDROXY:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ARYL HYDROCARBON HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	ELLIPTICINE,9-FLUORO:	WEAK ACTIVITY

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