Experiment 1176165

Worktypes

CARCINOGENIC DATA (MARKER CODE)EFFECTS DUE TO A COMBINATION OF DRUGSPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ELLIPTICINE,9-HYDROXY:

Details

PropertyValue
Pharmacology
COMUTAGENIC ACTIVITY
OrganismEmpty organism
CitationCRESTEIL,T: LESCA,P:. (1983). ENHANCEMENT OF DNA BINDING, MUTAGENICITY AND CARCINOGENICITY OF POLYCYCLIC AROMATIC HYDROCARBONS AFTER INDUCTION OF CYTOCHROME P-450 BY ELLIPTICINES IN RATS AND MICE.. 47(2)
Amount utilized
Compound isolated
DiseaseBENZOPYRENE MUTAGENESIS WAS SIGNIFICANTLY ENHANCED IN THIS ASSAY WHEN GIVEN WITH S9 MIX FROM 9-HYDROXYELLIPTICINE TREATED MICE.
Dose amountVAR
Number3
Qualitative resultACTIVE
AnimalAGAR PLATE
Dose expressionCONC USED