Citation 179487

THURSTON,LS: IRIE,H: TANI,S: HAN,FS: LIU,ZC: CHENG,YC: LEE,KH:. (1986). ANTITUMOR AGENTS. 78. INHIBITION OF HUMAN DNA TOPOISOMERASE II BY PODOPHYLLOTOXIN AND ALPHA-PELTATIN ANALOGUES.. 29()

Citation Details

Title	ANTITUMOR AGENTS. 78. INHIBITION OF HUMAN DNA TOPOISOMERASE II BY PODOPHYLLOTOXIN AND ALPHA-PELTATIN ANALOGUES.
Authors	THURSTON,LS: IRIE,H: TANI,S: HAN,FS: LIU,ZC: CHENG,YC: LEE,KH:
Year	1986
Volume	29
Issue

Summary

Year: 1986

Journal: Unknown

Organisms and Their Experiments (1)

Podophyllum peltatum (BERBERIDACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OF	PELTATIN,ALPHA:	None
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PELTATIN,ALPHA:	INACTIVE
3	Not specified	PMR SPECTRUM REPORTED	PELTATIN,ALPHA: DIACETATE*	None
4	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PELTATIN,ALPHA: DIACETATE*	WEAK ACTIVITY
5	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ETOPOSIDE*	ACTIVE
6	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,PICRO:	INACTIVE
7	Not specified	PMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	PELTATIN,ALPHA: 6-7-DE-O-METHYLENE: TETRAACETATE*	None
8	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PELTATIN,ALPHA: 6-7-DE-O-METHYLENE: TETRAACETATE*	WEAK ACTIVITY
9	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	PELTATIN,ALPHA: 6-7-DE-O-METHYLENE:*	None
10	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PELTATIN,ALPHA: 6-7-DE-O-METHYLENE:*	ACTIVE
11	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	PODOPHYLLOTOXIN,EPI: 3'-4'-DIDEMETHYL:	None
12	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 3'-4'-DIDEMETHYL:	ACTIVE
13	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI:	WEAK ACTIVITY
14	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	PODOPHYLLIN,BETA-APOPICRO: 4'-DEMETHYL:*	None
15	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLIN,BETA-APOPICRO: 4'-DEMETHYL:*	NOT POSSIBLE TO INTERPRET RESULTS
16	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTED	PODOPHYLLOTOXIN,EPI: 4-ETHYL ETHER: 4'-DEMETHYL:	None
17	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 4-ETHYL ETHER: 4'-DEMETHYL:	ACTIVE
18	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL:	None
19	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL:	ACTIVE
20	Not specified	ISOLATION AND IDENTIFICATION OF	PODOPHYLLOTOXIN	None
21	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN	INACTIVE
22	Not specified	ISOLATION AND IDENTIFICATION OF	PELTATIN,BETA:	None
23	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PELTATIN,BETA:	INACTIVE
24	Not specified	ISOLATION AND IDENTIFICATION OF	PODOPHYLLOTOXIN,4'-DEMETHYL:	None
25	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL:	INACTIVE

Citation 179487

Citation Details

Summary

Organisms and Their Experiments (1)

Podophyllum peltatum (BERBERIDACEAE)

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