Experiment 1180690

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PODOPHYLLOTOXIN,EPI: 4-ETHYL ETHER: 4'-DEMETHYL:

Details

PropertyValue
Pharmacology
TOPOISOMERASE II INHIBITION
OrganismPodophyllum peltatum (BERBERIDACEAE)
CitationTHURSTON,LS: IRIE,H: TANI,S: HAN,FS: LIU,ZC: CHENG,YC: LEE,KH:. (1986). ANTITUMOR AGENTS. 78. INHIBITION OF HUMAN DNA TOPOISOMERASE II BY PODOPHYLLOTOXIN AND ALPHA-PELTATIN ANALOGUES.. 29()
Amount utilized
Compound isolated
Dose amount0.4 MILLIMOLS
Number17
Qualitative resultACTIVE
Dose expressionCONC USED