Citation 77991

GOLAKOTI,T: OGINO,J: HELTZEL,CE: LE HUSEBO,T: JENSEN,CM: LARSEN,LK: PATTERSON,GML: MOORE,RE: MOOBERRY,SL: CORBETT,TH: VALERIOTE,FA:. (1995). STRUCTURE DETERMINATION, CONFORMATIONAL ANALYSIS, CHEMICAL STABILITY STUDIES, AND ANTITUMOR EVALUATION OF THE CRYPTOPHYCINS. ISOLATION OF 18 NEW ANALOGS FROM NOSTOC SP. STRAIN GSV 224.. 117(49)

Citation Details

TitleSTRUCTURE DETERMINATION, CONFORMATIONAL ANALYSIS, CHEMICAL STABILITY STUDIES, AND ANTITUMOR EVALUATION OF THE CRYPTOPHYCINS. ISOLATION OF 18 NEW ANALOGS FROM NOSTOC SP. STRAIN GSV 224.
AuthorsGOLAKOTI,T: OGINO,J: HELTZEL,CE: LE HUSEBO,T: JENSEN,CM: LARSEN,LK: PATTERSON,GML: MOORE,RE: MOOBERRY,SL: CORBETT,TH: VALERIOTE,FA:
Year1995
Volume117
Issue49

Summary

Year: 1995

Journal: Unknown

Organisms and Their Experiments (1)

Nostoc species (NOSTOCACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
ISOLATION AND IDENTIFICATION OFSTRUCTURE DETERMINATION OFABSOLUTE CONFIGURATION DETERMINEDSTABILITY STUDIES OF
CRYPTOPHYCIN 1
None
2
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 1
STRONG ACTIVITY
3
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 1
STRONG ACTIVITY
4
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 1
STRONG ACTIVITY
5Not specified
ISOLATION AND IDENTIFICATION OFSTRUCTURE DETERMINATION OFQUANTITATIVE DATA
CRYPTOPHYCIN 2
None
6Not specified
ISOLATION AND IDENTIFICATION OFABSOLUTE CONFIGURATION DETERMINEDX-RAY CHRYSTALLOGRAPHIC STUDIESQUANTITATIVE DATA
CRYPTOPHYCIN 3
None
7
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 2
STRONG ACTIVITY
8
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 2
STRONG ACTIVITY
9
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 2
STRONG ACTIVITY
10
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 3
STRONG ACTIVITY
11
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 3
STRONG ACTIVITY
12
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 3
STRONG ACTIVITY
13Not specified
ISOLATION AND IDENTIFICATION OFSTRUCTURE DETERMINATION OFQUANTITATIVE DATA
CRYPTOPHYCIN 4
None
14Not specified
ISOLATION AND IDENTIFICATION OFSTRUCTURE DETERMINATION OFABSOLUTE CONFIGURATION DETERMINED
CRYPTOPHYCIN 5
None
15
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 4
STRONG ACTIVITY
16
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 4
STRONG ACTIVITY
17
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 4
STRONG ACTIVITY
18
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 5
STRONG ACTIVITY
19
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 5
STRONG ACTIVITY
20
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 5
STRONG ACTIVITY
21Not specified
ABSOLUTE CONFIGURATION DETERMINEDSTABILITY STUDIES OFISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 8
None
22Not specified
STABILITY STUDIES OFISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 15
None
23
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 8
STRONG ACTIVITY
24
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 8
STRONG ACTIVITY
25
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 8
STRONG ACTIVITY
26
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 15
STRONG ACTIVITY
27
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 15
STRONG ACTIVITY
28
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 15
STRONG ACTIVITY
29Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 16
None
30Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 17
None
31
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 16
STRONG ACTIVITY
32
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 16
STRONG ACTIVITY
33
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 16
STRONG ACTIVITY
34
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 17
STRONG ACTIVITY
35
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 17
STRONG ACTIVITY
36
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 17
STRONG ACTIVITY
37Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 18
None
38Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 19
None
39
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 18
STRONG ACTIVITY
40
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 18
STRONG ACTIVITY
41
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 18
STRONG ACTIVITY
42
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 19
STRONG ACTIVITY
43
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 19
STRONG ACTIVITY
44
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 19
STRONG ACTIVITY
45Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 21
None
46
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 21
STRONG ACTIVITY
47
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 21
STRONG ACTIVITY
48
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 21
STRONG ACTIVITY
49Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 23
None
50Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 24
None
51
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 23
STRONG ACTIVITY
52
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 23
STRONG ACTIVITY
53
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 23
STRONG ACTIVITY
54
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 24
STRONG ACTIVITY
55
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 24
STRONG ACTIVITY
56
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 24
STRONG ACTIVITY
57Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 25
None
58Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 26
None
59
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 25
STRONG ACTIVITY
60
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 25
STRONG ACTIVITY
61
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 25
STRONG ACTIVITY
62
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 26
STRONG ACTIVITY
63
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 26
STRONG ACTIVITY
64
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 26
ACTIVE
65Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 28
None
66Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 29
None
67
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 28
STRONG ACTIVITY
68
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 28
STRONG ACTIVITY
69
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 28
STRONG ACTIVITY
70
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 29
STRONG ACTIVITY
71
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 29
STRONG ACTIVITY
72
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 29
STRONG ACTIVITY
73Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 30
None
74Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 31
None
75
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 30
STRONG ACTIVITY
76
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 30
STRONG ACTIVITY
77
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 30
STRONG ACTIVITY
78
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 31
STRONG ACTIVITY
79
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 31
STRONG ACTIVITY
80
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 31
STRONG ACTIVITY
81Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 40
None
82Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 43
None
83
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 40
STRONG ACTIVITY
84
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 40
STRONG ACTIVITY
85
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 40
STRONG ACTIVITY
86
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 43
STRONG ACTIVITY
87
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 43
STRONG ACTIVITY
88
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 43
STRONG ACTIVITY
89Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 45
None
90Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 49
None
91
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 45
STRONG ACTIVITY
92
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 45
STRONG ACTIVITY
93
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 45
STRONG ACTIVITY
94
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 49
STRONG ACTIVITY
95
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 49
STRONG ACTIVITY
96
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 49
STRONG ACTIVITY
97Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 50
None
98Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
CRYPTOPHYCIN 54
None
99
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 50
STRONG ACTIVITY
100
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 50
STRONG ACTIVITY
101
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 50
STRONG ACTIVITY
102
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 54
STRONG ACTIVITY
103
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 54
STRONG ACTIVITY
104
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE
CRYPTOPHYCIN 54
STRONG ACTIVITY
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