Experiment 201453

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CRYPTOPHYCIN 24

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismNostoc species (NOSTOCACEAE)
CitationGOLAKOTI,T: OGINO,J: HELTZEL,CE: LE HUSEBO,T: JENSEN,CM: LARSEN,LK: PATTERSON,GML: MOORE,RE: MOOBERRY,SL: CORBETT,TH: VALERIOTE,FA:. (1995). STRUCTURE DETERMINATION, CONFORMATIONAL ANALYSIS, CHEMICAL STABILITY STUDIES, AND ANTITUMOR EVALUATION OF THE CRYPTOPHYCINS. ISOLATION OF 18 NEW ANALOGS FROM NOSTOC SP. STRAIN GSV 224.. 117(49)
Amount utilized
Compound isolated
Dose amount0.499 NANOMOLS
Number56
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50