Citation 82814

FUKUDA,K: OHTA,T: OSHIMA,Y: OHASHI,N: YOSHIKAWA,M: YAMAZOE,Y:. (1997). SPECIFIC CYP3A4 INHIBITORS IN GRAPEFRUIT JUICE: FUROCOUMARIN DIMERS AS COMPONENTS OF DRUG INTERACTION.. 7(5)

Citation Details

Title	SPECIFIC CYP3A4 INHIBITORS IN GRAPEFRUIT JUICE: FUROCOUMARIN DIMERS AS COMPONENTS OF DRUG INTERACTION.
Authors	FUKUDA,K: OHTA,T: OSHIMA,Y: OHASHI,N: YOSHIKAWA,M: YAMAZOE,Y:
Year	1997
Volume	7
Issue	5

Summary

Year: 1997

Journal: Unknown

Organisms and Their Experiments (1)

Citrus paradisi (RUTACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TESTOSTERONE HYDROXYLASE INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
2	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	BENZOPYRAN-7-ONE,4-[[6-HYDROXY-7-[[1-[(1-HYDROXY-1-METHYL)-ETHYL]-4-METHYL-6-(7-OXO-7(H)-FUROL[3-2-G][1]-BENZOPYRAN-4-YL)-4-HEXENYLI-OXY]-3-7-DIMETHYL-2-OCTENYL]-OXY]-7(H)-FUROL[3-2-G]-[1]:	None
3	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BENZOPYRAN-7-ONE,4-[[6-HYDROXY-7-[[1-[(1-HYDROXY-1-METHYL)-ETHYL]-4-METHYL-6-(7-OXO-7(H)-FUROL[3-2-G][1]-BENZOPYRAN-4-YL)-4-HEXENYLI-OXY]-3-7-DIMETHYL-2-OCTENYL]-OXY]-7(H)-FUROL[3-2-G]-[1]:	STRONG ACTIVITY
4	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	BENZOPYRAN-7-ONE,4-[[6-HYDROXY-7-[[4-METHYL-1-(1-METHYL-ETHENYL)-6-(7-OXO-7(H)-FUROL[3-2-G][1]-BENZOPYRAN-4-YL)-4-HEXENYL]-OXY]-3-7-DIMETHYL-2-OCTENYL]-OXY]-7(H)-FUROL[3-2-G]-[1]	None
5	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BENZOPYRAN-7-ONE,4-[[6-HYDROXY-7-[[4-METHYL-1-(1-METHYL-ETHENYL)-6-(7-OXO-7(H)-FUROL[3-2-G][1]-BENZOPYRAN-4-YL)-4-HEXENYL]-OXY]-3-7-DIMETHYL-2-OCTENYL]-OXY]-7(H)-FUROL[3-2-G]-[1]	STRONG ACTIVITY
6	Not specified	ISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTED	BERGAMOTTINNOOTKATONECOUMARIN,GERANYL-OXY:	None
7	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BERGAMOTTINNOOTKATONECOUMARIN,GERANYL-OXY:	ACTIVE

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