Experiment 239133

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BENZOPYRAN-7-ONE,4-[[6-HYDROXY-7-[[1-[(1-HYDROXY-1-METHYL)-ETHYL]-4-METHYL-6-(7-OXO-7(H)-FUROL[3-2-G][1]-BENZOPYRAN-4-YL)-4-HEXENYLI-OXY]-3-7-DIMETHYL-2-OCTENYL]-OXY]-7(H)-FUROL[3-2-G]-[1]:

Details

PropertyValue
Pharmacology
CYTOCHROME P450 INHIBITION
OrganismCitrus paradisi (RUTACEAE)
CitationFUKUDA,K: OHTA,T: OSHIMA,Y: OHASHI,N: YOSHIKAWA,M: YAMAZOE,Y:. (1997). SPECIFIC CYP3A4 INHIBITORS IN GRAPEFRUIT JUICE: FUROCOUMARIN DIMERS AS COMPONENTS OF DRUG INTERACTION.. 7(5)
Amount utilized
Compound isolated
DiseaseEFFECT MEASURED BY TESTOSTERONE 6-BETA HYDROXYLATION.
Number3
Qualitative resultSTRONG ACTIVITY
Dose expressionCONC USED