Citation 90465

COREA,G: FATTORUSSO,E: LANZOTTI,V: TAGLIALATELA-SCAFATI,O: APPENDINO,G: BALLERO,M: SIMON,PN: DUMONTET,C: DI PIETRO,A:. (2003). JATROPHANE DITERPENES AS P-GLYCOPROTEIN INHIBITORS. FIRST INSIGHTS OF STRUCTURE-ACTIVITY RELATIONSHIPS AND DISCOVERY OF A NEW, POWERFUL LEAD.. 46()

Citation Details

TitleJATROPHANE DITERPENES AS P-GLYCOPROTEIN INHIBITORS. FIRST INSIGHTS OF STRUCTURE-ACTIVITY RELATIONSHIPS AND DISCOVERY OF A NEW, POWERFUL LEAD.
AuthorsCOREA,G: FATTORUSSO,E: LANZOTTI,V: TAGLIALATELA-SCAFATI,O: APPENDINO,G: BALLERO,M: SIMON,PN: DUMONTET,C: DI PIETRO,A:
Year2003
Volume46
Issue

Summary

Year: 2003

Journal: Unknown

Organisms and Their Experiments (1)

Euphorbia dendroides (EUPHORBIACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
VOUCHER SPECIMEN REPORTED FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN A
None
2
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN A
ACTIVE
3Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN B
None
4
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN B
ACTIVE
5Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN D
None
6
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN D
STRONG ACTIVITY
7Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN F
None
8
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN F
ACTIVE
9Not specified
ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA
JATROPHA-6(17)-TRANS-11-DIEN-14-ONE,2-3-5-7-8-9-15-HEPTAHYDROXY: 2-5-8-9-TETAACETATE-3-(PHENOXY-ACETYL)-7-ISOBUTYL: (2R-3R-4R-5R-7S-8S-9S-13S-15S):
None
10
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
JATROPHA-6(17)-TRANS-11-DIEN-14-ONE,2-3-5-7-8-9-15-HEPTAHYDROXY: 2-5-8-9-TETAACETATE-3-(PHENOXY-ACETYL)-7-ISOBUTYL: (2R-3R-4R-5R-7S-8S-9S-13S-15S):
WEAK ACTIVITY
11Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN G
None
12
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN G
ACTIVE
13Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN H
None
14
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN H
WEAK ACTIVITY
15Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN I
None
16
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN I
WEAK ACTIVITY
17Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN E
None
18
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN E
ACTIVE
19Not specified
MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
EUPHODENDROIDIN C
None
20
DAUNOMYCIN EFFLUX INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
EUPHODENDROIDIN C
WEAK ACTIVITY
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