Experiment 308117

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

JATROPHA-6(17)-TRANS-11-DIEN-14-ONE,2-3-5-7-8-9-15-HEPTAHYDROXY: 2-5-8-9-TETAACETATE-3-(PHENOXY-ACETYL)-7-ISOBUTYL: (2R-3R-4R-5R-7S-8S-9S-13S-15S):

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
DAUNOMYCIN EFFLUX INHIBITION
OrganismEuphorbia dendroides (EUPHORBIACEAE)
CitationCOREA,G: FATTORUSSO,E: LANZOTTI,V: TAGLIALATELA-SCAFATI,O: APPENDINO,G: BALLERO,M: SIMON,PN: DUMONTET,C: DI PIETRO,A:. (2003). JATROPHANE DITERPENES AS P-GLYCOPROTEIN INHIBITORS. FIRST INSIGHTS OF STRUCTURE-ACTIVITY RELATIONSHIPS AND DISCOVERY OF A NEW, POWERFUL LEAD.. 46()
Amount utilized
Compound isolated
Dose amountVAR
Number10
Qualitative resultWEAK ACTIVITY
Dose expressionCONC USED