Experiment 1038196

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BRUCEOLIDE,3-(3-4-DIMETHYL-2-PENTONYL):

Alerts

RESULTS SIGNIFICANT AT P < 0.005 LEVEL.

Details

PropertyValue
Pharmacology
DIHYDROFOLATE REDUCTASE INHIBITION
OrganismEmpty organism
CitationHALL,IH: LIOU,YF: OKANO,M: LEE,KH:. (1982). ANTITUMOR AGENTS 46: IN VITRO EFFECTS OF ESTERS OF BRUSATOL,BISBRUSATOL,AND RELATED COMPOUNDS ON NUCLEIC ACID PROTEIN SYNTHESIS OF P-388 LYMPHOCYTIC LEUKEMIA CELLS.. 71()
Amount utilized
Compound isolated
Disease19% INHIBITION.
Dose amount10.0 MICROMOLS
Number3
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionCONC USED