Experiment 1038247

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BRUSATOLYL,BIS-12-12'-DIACETYL: SUCCINATE

Alerts

RESULTS SIGNIFICANT AT P < 0.01 LEVEL.

Details

PropertyValue
Pharmacology
DIHYDROFOLATE REDUCTASE INHIBITION
OrganismEmpty organism
CitationHALL,IH: LIOU,YF: OKANO,M: LEE,KH:. (1982). ANTITUMOR AGENTS 46: IN VITRO EFFECTS OF ESTERS OF BRUSATOL,BISBRUSATOL,AND RELATED COMPOUNDS ON NUCLEIC ACID PROTEIN SYNTHESIS OF P-388 LYMPHOCYTIC LEUKEMIA CELLS.. 71()
Amount utilized
Compound isolated
Disease28% INHIBITION.
Dose amount10.0 MICROMOLS
Number6
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionCONC USED